Net profit for the three months through Sept. 30 dropped to US$34.7 million (US$24 million) from US$87.2 million in the same period a year earlier. Sales rose 35 percent to US$608.7 million (US$421.4 million), Shire said in a statement.
The company also raised its forecast for full-year revenue growth of 30 percent. Shire had previously forecast growth of "at least 25 percent."
"We have continued to execute on our strategy as a specialty biopharmaceutical company and made significant progress with all of our product launches," said Chief Executive Matthew Emmens.
The company makes other drugs to treat attention deficit hyperactivity disorder, such as Vyvanse and Daytrana, as well as human genetic therapies and gastrointestinal and renal disease treatments.
Shire shares gained 0.3 percent to 1,205 pence (US$24.97; €17.28) on the London Stock Exchange.
"We should use shock therapy to sober up the Americans. In this case, the Americans will speak about the need to resume dialogue. There is no other option"
The United States is concerned about the current crisis in the relations with Russia and suggests returning to reasonable policies to avoid a nuclear war