Net profit for the three months through Sept. 30 dropped to US$34.7 million (US$24 million) from US$87.2 million in the same period a year earlier. Sales rose 35 percent to US$608.7 million (US$421.4 million), Shire said in a statement.
The company also raised its forecast for full-year revenue growth of 30 percent. Shire had previously forecast growth of "at least 25 percent."
"We have continued to execute on our strategy as a specialty biopharmaceutical company and made significant progress with all of our product launches," said Chief Executive Matthew Emmens.
The company makes other drugs to treat attention deficit hyperactivity disorder, such as Vyvanse and Daytrana, as well as human genetic therapies and gastrointestinal and renal disease treatments.
Shire shares gained 0.3 percent to 1,205 pence (US$24.97; €17.28) on the London Stock Exchange.
Near the United Nations Glass Palace in New York, there is a metallic sculpture entitled "Evil Defeated by Good", representing Saint George transfixing a dragon with his lance. It was donated by the USSR in 1990 to celebrate the INF Treaty concluded with the USA in 1987