The Seattle Biomedical Research Institute will pay volunteers as much as $4,000 to be bitten by mosquitoes infected with malaria. Malaria is one of the most common infectious diseases and an enormous public health problem.
Scientists say no lives are in danger because the volunteers can be cured. The institute is testing which vaccines work fastest.
The head of the program, Dr. Patrick Duffy, says volunteers will spend several nights under medical supervision in a hotel.
All of the human trials will be reviewed for safety by the Food and Drug Administration.
Malaria is a vector-borne infectious disease caused by protozoan parasites. It is widespread in tropical and subtropical regions, including parts of the Americas, Asia, and Africa. Each year, it causes disease in approximately 515 million people and kills between one and three million people, the majority of whom are young children in Sub-Saharan Africa. Malaria is commonly associated with poverty, but is also a cause of poverty and a major hindrance to economic development.
Treatment of malaria involves supportive measures as well as specific antimalarial drugs. When properly treated, someone with malaria can expect a complete cure.