Source Pravda.Ru

Negative Effect Of Tysabri Under Scrutiny

    Researchers explain the cases of  sometimes-fatal side effect of Biogen Idec Inc.’s Tysabri, a treatment for multiple sclerosis, through its wrong influence on a type of cell. It turns out that  the drug makes a type of cell in patients’ immune systems less effective against a virus.

   The result is a brain disorder called progressive multifocal leukoencephalopathy or PML, which occurs after the virus defeats immune defenses, mutates and penetrates the brain. Researchers led by Igor Koralnik, a Harvard Medical School neurologist in Boston, found that patients taking Tysabri had increases in the virus in their blood and urine, according to a report released today by the New England Journal of Medicine.

    Tysabri’s link to PML prompted the U.S. Food and Drug Administration to suspend the product’s sales in 2005, leading patients to plea for, and win, the product’s return. While the study identifies why the drug may enable the illness in patients taking Tysabri, the research doesn’t show a way to detect who may be most at risk for PML, said Eugene Major, the author of a related editorial in the journal.

    Multiple sclerosis (abbreviated MS, also known as disseminated sclerosis or encephalomyelitis disseminata) is an autoimmune disease in which the body's immune response attacks a person's central nervous system (brain and spinal cord), leading to demyelination. Disease onset usually occurs in young adults, and it is more common in females.

Comments
Israel vows to destroy Russia's S-300 in Syria in case of danger
Israel vows to destroy Russia's S-300 in Syria in case of danger
America always thirsty for more blood that even children can shed
America always thirsty for more blood that even children can shed
Russia's S-300 systems against Tomahawk missiles flying towards Syria
Russia to deliver S-300 air defence systems to Syria for free
Russia's S-300 systems against Tomahawk missiles flying towards Syria
Silk Road To Germany: New Molotov-Ribbentrop-Mao Pact
Silk Road To Germany: New Molotov-Ribbentrop-Mao Pact
Silk Road To Germany: New Molotov-Ribbentrop-Mao Pact
Silk Road To Germany: New Molotov-Ribbentrop-Mao Pact
Oil prices ups and downs: Russia wins if Iran loses
Israel vows to destroy Russia's S-300 in Syria in case of danger
Israel vows to destroy Russia's S-300 in Syria in case of danger
Israel vows to destroy Russia's S-300 in Syria in case of danger
Israel vows to destroy Russia's S-300 in Syria in case of danger
Israel vows to destroy Russia's S-300 in Syria in case of danger
Silk Road To Germany: New Molotov-Ribbentrop-Mao Pact
Russia to deliver S-300 air defence systems to Syria for free
Silk Road To Germany: New Molotov-Ribbentrop-Mao Pact
Israel vows to destroy Russia's S-300 in Syria in case of danger