Source Pravda.Ru

Unique study gives surmises about Childhood leukaemia's cause

Professor Tariq Enver, from Medical Research Council Molecular Haematology Unit in Oxford, and Professor Mel Greaves, from Institute of Cancer Research, have made serious steps in the way of diagnosing, treating and avoiding the risk of relapse of the most ruthless disease - childhood leukaemia.

Leukemia or leukaemia is a cancer of the blood or bone marrow and is characterized by an abnormal proliferation (production by multiplication) of blood cells, usually white blood cells (leukocytes).

Leukemia, like other cancers, result from somatic mutations in the DNA which activate oncogenes or deactivate tumor suppressor genes, and disrupt the regulation of cell death, differentiation or division. These mutations may occur spontaneously or as a result of exposure to radiation or carcinogenic substances and are likely to be influenced by genetic factors.

The researchers studied four-year-old twin girls, Olivia and Isabella, with pre-leukaemic stem cells, to date Olivia has developed leukaemia (acute lymphoblastic leukaemia), while her sister has not.

But to have pre-leukaemic stem cells is not enough, another genetic mutation must take place for the cells to cause disease. In Olivia’s case it might have been infection.

Until the cause or causes of leukemia are found, there is no way to prevent the disease. Even when the causes become known, they may prove to be things which are not readily controllable, such as naturally occurring background radiation, and therefore not especially helpful for prevention purposes.

The researchers think that for now the best way of treating the disease and avoiding the relapse is to attack the pre-leukaemic cells in children with leukaemia.

The “twin-study” is really unique as it is still unknown why one child has developed the disease and the other hasn’t.

Comments
Russian Defense Minister speaks about war with Ukraine, US and fight for Crimea
Russian Defense Minister speaks about war with Ukraine, US and fight for Crimea
Russian Defense Minister speaks about war with Ukraine, US and fight for Crimea
Ukraine dreams of what it can do to Crimea after winning war with Russia
Default more likely to hit American, rather than Russian economy
The Sham called Democracy
The Sham called Democracy
Russian woman killed when hanging out naked of moving car in Dominican Republic
Pilot shares his impressions after flying Su-57 fifth-generation fighter
Russian government prepares to get rid of US dollar in economy
Putin in Austria: Europe doesn't like Russia very much, but it is fed up with USA too
US-Russian confrontation: War is peace, freedom is slavery
Details of Putin-Merkel surprise meeting unveiled
Russia's long-range Bastion system follows USS Carney in Black Sea waters
The insane idea in Germany: "pedophilia normal love"
US sanctions to kill Russian banks and sovereign debt?
Will Smith tells of his trip to Russia in a video
Why Russia continues investing in US public debt
USA and Turkey: The elephant kicks the barking pug aside
In Ukraine, human organs don't stink
US-Russian confrontation: War is peace, freedom is slavery