The 33-year-old rapper, whose real name is Shawntae Harris, was arrested early Thursday after officers answered a call to Studio 72 northeast of Atlanta about a pushing incident.
Harris and a 24-year-old waitress at the club got into an argument after she bumped into Harris, said DeKalb County police spokeswoman Mekka Parish, citing the police report. At some point, the waitress walked away and moments later was hit in the face with the bottle of rum. She sustained a deep laceration to the cheek and some swelling on the forehead.
Harris was released from county jail after posting a $50,000 bond Thursday night, said Parish.
Hits by Da Brat include the song "Funkdafied." She also has appeared on reality shows such as "Celebrity Fit Club" and "The Surreal Life."
Harris was the first female rapper to have a platinum-selling album.
Police said her address is listed as Chicago.