Source AP ©

Drug Prexige may cause liver damage

Anti-inflammatory drug Prexige is called off the market Thursday due to the potential risk of causing serious liver-related adverse events.

Health Canada said sales and market authorization of the drug will be stopped for lumiracoxib, which is sold by Novartis Pharmaceuticals Canada Inc. as Prexige.

Prexige treats acute and chronic signs and symptoms of knee osteoarthritis in adults. In July of this year its approval was widened to include treatment of general osteoarthritis in adults.

Prexige, which was approved for sale in Canada less than a year ago, has recently been linked to rare but serious liver problems in some users. Two such cases have been reported in Canada.

Australia's drug regulatory agency, the Therapeutic Goods Administration, removed Prexige from its market in August after eight reports of side-effects involving serious liver problems when people took Prexige in 200 milligram and 400 mg doses daily. Two of the people involved died and two required liver transplants.

Following the Australian decision, Health Canada undertook a review of the drug's safety data. In its statement Thursday the drug regulator said it had reached the conclusion the risk of serious liver-related adverse events cannot be safely managed at the 100 mg daily dose, which Canada had set as the drug's daily maximum dose.

The co-author of this disaster is the Dutch government, which did not find either strength or desire to save the lives of its citizens who were flying on that plane. The Dutch authorities did not demand Ukraine to comply with international aviation regulations

Blame MH17 on Russia: International investigation turns into demonic circus

The co-author of this disaster is the Dutch government, which did not find either strength or desire to save the lives of its citizens who were flying on that plane. The Dutch authorities did not demand Ukraine to comply with international aviation regulations

Blame MH17 on Russia: International investigation turns into demonic circus

On the second day of the St. Petersburg International Economic Forum, a plenary meeting was held, in which Russian President Vladimir Putin, French President Emmanuel Macron, Japanese Prime Minister Shinzo Abe, Chinese Vice President Wang Qishan and IMF head Christine Lagarde took part

World leaders unite with Russia at St. Petersburg International Economic Forum
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Blame MH17 on Russia: International investigation turns into demonic circus
Blame MH17 on Russia: International investigation turns into demonic circus
Blame MH17 on Russia: International investigation turns into demonic circus
Blame MH17 on Russia: International investigation turns into demonic circus
Blame MH17 on Russia: International investigation turns into demonic circus
Blame MH17 on Russia: International investigation turns into demonic circus
Blame MH17 on Russia: International investigation turns into demonic circus
Blame MH17 on Russia: International investigation turns into demonic circus
Blame MH17 on Russia: International investigation turns into demonic circus
Blame MH17 on Russia: International investigation turns into demonic circus
Blame MH17 on Russia: International investigation turns into demonic circus
Blame MH17 on Russia: International investigation turns into demonic circus