Source Pravda.Ru

Congress requests Merck and Schering to hand over Vytorin data

By Margarita Snegireva. Congress today sent letters requesting that Food and Drug Administration commissioner Andrew von Eschenbach and executives of the drug companies Merck and Schering-Plough hand over documents detailing the marketing campaign for the cholesterol drug Vytorin.

The results of a clinical trial released Monday found that Vytorin did not reduce the buildup of harmful plaque in arteries any better than a much cheaper generic drug.

Ezetimibe/simvastatin is a drug combination used for the treatment of dyslipidemia. It is a combination of ezetimibe (best known as Zetia in the United States) and the statin drug simvastatin (best known as Zocor in the U.S.). The combination preparation is marketed by Merck & Co./Schering-Plough Pharmaceuticals (joint venture) under the trade names Vytorin and Inegy.

Ezetimibe is prescribed to reduce the amount of cholesterol that the body absorbs from the food ingested. But a recent study by the drug's manufacturers revealed that it did not reduce the buildup of plaque in the coronary arteries -- a key indicator of progression toward heart disease.

Simvastatin is an HMG-CoA reductase inhibitor or statin. It works by blocking an enzyme that is necessary for the body to make cholesterol.

Comments
IOC wants Russia to boycott 2018 Winter Games and exit Olympic movement
IOC wants Russia to boycott 2018 Winter Games and exit Olympic movement
IOC wants Russia to boycott 2018 Winter Games and exit Olympic movement
Ticking Time Bomb: Countdown to Armageddon
Ukraine's Western allies point their guns at President Poroshenko
IOC wants Russia to boycott 2018 Winter Games and exit Olympic movement
A Europe without roots now also demolishes churches
The Green Africa project
It is about time Russia should exit Western project
Honor me: The hell with you
Student barred from exams at Moscow State University for wearing Jewish hat
Student barred from exams at Moscow State University for wearing Jewish hat
China wants Moscow to confront pressure from Washington together
British army chief says Russia can destroy UK sooner than expected
Ticking Time Bomb: Countdown to Armageddon
British army chief says Russia can destroy UK sooner than expected
Russia's new torpedo carrying 100-megaton nuclear warhead nullifies USA's Prompt Global Strike
About the New Year Address of Marshal Kim Jong Un
It is about time Russia should exit Western project
About the New Year Address of Marshal Kim Jong Un
About the New Year Address of Marshal Kim Jong Un