"Ever since I was a little girl, before it even started in 1980 - MTV - I said, `Someday, I want there to be an all-music channel that gives out awards for movies. And I want to host that show,"' the 36-year-old actress-comedian said in an interview with The Associated Press.
The show will air live June 3 from the Gibson Amphitheatre in Los Angeles.
How is Silverman preparing for her new gig?
"I'm getting ready," she said. "I'm exercising every day and I do 10 push-ups, I do eight sit-ups and then I rinse off. ... I want to go just a little bit too far."
"I'm training for this the way what's-her-face trained for `T2,"' said Silverman, referring to Linda Hamilton in "Terminator 2: Judgment Day."
Silverman has her own Comedy Central series, "The Sarah Silverman Program." She also starred in a feature film-length version of her one-woman show, "Sarah Silverman: Jesus Is Magic."
Despite her experience in front of an audience, it's "starting to sink in" that the 16th annual ceremony will be live for the first time, she said.
"I mean, I'm not a big swearer or anything, but I still seem to say things that you can't say on basic cable, so ... we're gonna have to have, like, a plan," she said.
MTV President Christina Norman praised Silverman's irreverence and "no holds barred sarcasm."
Mark Burnett, whose series include "Survivor" and "The Apprentice," is the executive producer of this year's ceremony.