The visit to Rome is the first leg of the Egyptian president's tour of European capitals that includes Berlin and Vienna.
Mubarak is expected to meet Monday with Pope Benedict XVI at the Vatican on his way back to Egypt. The pontiff suspended all his audiences this week to perform spiritual exercises at the start of the Roman Catholic Church's solemn Lenten season.
Mubarak was scheduled to meet Thursday with Italian President Carlo Azeglio Ciampi and then with Berlusconi at the premier's office. The Middle East and the fight against international terrorism were expected to top the agenda of the talks.
Berlusconi has previously praised Egypt as an indispensable partner in efforts to combat terror, reports the AP.
The Investigative Committee of the Russian Federation put the head of the contractor company of Russia's space corporation Roskosmos, Sergei Slastikhin, on international wanted list
"Washington operators of the sanctions machine ought to get acquainted with the history of Russia, to stop the unnecessary fussing," spokesperson for the Foreign Ministry said